LIfestyle Modification Helps Erectile Dysfunction

Wednesday, September 14, 2011 // Uncategorized

Men often worry that taking cholesterol lowering medication or blood pressure medication will cause erectile dysfunction.  This can be a side effect of some older medications, but this recent study outlined in Journal Watch details how treating the risk factors for heart disease with lifestyle modification and medication can improve erectile function.

 Treating Cardiovascular Risk Factors Can Improve Sexual Function in Men with ED

Using lifestyle modification or drug therapy to treat cardiovascular risk factors can ameliorate erectile dysfunction, according to a meta-analysis in the Archives of Internal Medicine.
The meta-analysis included four randomized trials that looked at the effects of lifestyle modification (e.g., weight loss, exercise) and two trials that examined the impact of atorvastatin on CV risk factors and erectile dysfunction. Some 740 men were included, and follow-up ranged from 2 to 24 months.
Overall, reducing CV risk factors with either lifestyle changes or statin therapy was associated with statistically significant improvements in sexual function. The benefits persisted even when patients were also using phosphodiesterase type 5 inhibitors (e.g., sildenafil).
The researchers write: “Erectile dysfunction detection in the primary health clinic may provide an opportunity for early adoption of a healthy lifestyle to improve the overall health of men.”

Here is the abstract from The Archives of Internal Medicine:

The Effect of Lifestyle Modification and Cardiovascular Risk Factor Reduction on Erectile Dysfunction

A Systematic Review and Meta-analysis

Bhanu P. Gupta, MD; M. Hassan Murad, MD; Marisa M. Clifton, MD; Larry Prokop, MLS; Ajay Nehra, MD; Stephen L. Kopecky, MD

Arch Intern Med. Published online September 12, 2011. doi:10.1001/archinternmed.2011.440

Background  Erectile dysfunction (ED) shares similar modifiablerisks factors with coronary artery disease (CAD). Lifestylemodification that targets CAD risk factors may also lead toimprovement in ED. We conducted a systematic review and meta-analysisof randomized controlled trials evaluating the effect of lifestyleinterventions and pharmacotherapy for cardiovascular (CV) riskfactors on the severity of ED.

Methods  A comprehensive search of multiple electronic database through August 2010 was conducted using predefined criteria. We included randomized controlled clinical trials with follow-up of at least 6 weeks of lifestyle modification intervention or pharmacotherapy for CV risk factor reduction.Studies were selected by 2 independent reviewers. The main outcome  measure of the study is the weighted mean differences in the International Index of Erectile Dysfunction (IIEF-5) score with95% confidence intervals (CIs) using a random effects model.

Results  A total of 740 participants from 6 clinical trials in 4 countries were identified. Lifestyle modifications and pharmacotherapy for CV risk factors were associated with statistically significant improvement in sexual function (IIEF-5 score): weighted mean difference, 2.66 (95% CI, 1.86-3.47). If the trials     intervention (n = 143) are excluded, the remaining4 trials of lifestyle modification interventions (n = 597)demonstrate statistically significant improvement in sexual function: weighted mean difference, 2.40 (95% CI, 1.19-3.61).

Conclusion  The results of our study further strengthen the evidence that lifestyle modification and pharmacotherapy for CV risk factors are effective in improving sexual function in men with ED.

Interventions that are good for the heart are good for the brain and for erectile function.  Another reason to eat right, exercise and,  if necessary, take medication.


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