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Pneumonia Vaccine and Glucosamine News

Friday, October 29, 2010 // Uncategorized

10/7/2008 12:00:00 AM

Flu vaccination has been shown to reduce the risk of heart attacks.  Now comes word that the pneumonia vaccine (usually given to those over the age of 65 or those with chronic illnesses) may perform a similar service.

Pneumococcal Vaccine Linked to Lower MI Risk
Pneumococcal vaccination is associated with reduced risk for myocardial infarction in high-risk patients, according to a case-control study in the Canadian Medical Association Journal.
Using hospital and government databases, researchers studied some 5000 patients with at least one cardiovascular risk factor. Roughly 1000 patients who were admitted for MI were matched with 4000 admitted to surgical departments. After multivariable adjustment, patients who experienced an MI were less likely than controls to have received a pneumococcal polysaccharide vaccine within the past decade (odds ratio, 0.53). The protective effect was even greater in an analysis limited to vaccination more than 2 years previously (OR, 0.33)
In discussing possible mechanisms for the observed effect, the authors cite a mouse study in which vaccination interfered with the absorption of oxidized LDL by macrophages, “thereby interrupting an early and crucial step leading to atherosclerosis.”
CMAJ article (Free)
CMAJ commentary (Free)

Related Journal Watch link(s):

Many people swear by glucosamine.   See the previous post on chondroitan of April 17,2007.
Most take it in combination with chondoitan sulfate.  Evidence that it reduces arthritic pain is conflicting.  Many people take it in the hopes that it will retard the progression of osteoarthritis.  A recent study throws cold water on that.Glucosamine
Bottom line:  If it doesn’t choke you and it makes you feel better, take it.

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